After years of jealousy and resentment, sisters and aged former actresses Blanche (Joan Crawford) and 'Baby' Jane Hudson (Bette Davis) now live together in the same mansion. Beginning to suffer from mental illness, Jane begins to torment Blanche, who is confined to a wheelchair in her room, culminating in disaster for the two sisters. The film's sibling rivalry is fierce and tense, intensified by the actresses' own infamous rivalry with one another.