Irena Dubrovna (Simone Simon), a New York City--based fashion designer who hails from Serbia, begins a romance with marine engineer Oliver Reed (Kent Smith). After the couple gets married, Oliver becomes concerned about Irena's notion that she is cursed and may transform into a large cat in the heat of passion. Confiding in his beautiful assistant, Alice Moore (Jane Randolph), about his marital issues, Oliver unwittingly triggers Irena's curse, with tragic results.