American newlyweds Dr. Shane and June Brown (Vincent Gallo and Tricia Vessey) travel to Paris for their honeymoon. Once there, Shane begins a search for his former medical colleague Leo (Alex Descas), who may have information or a cure for the tropical virus that has transformed Leo's wife (Béatrice Dalle) into a murderous sexual carnivore, and may soon do the same to Shane. -The Film Desk/Vinegar Syndrome